Abstract
Background: The consumption of caffeine with and without sugar is endemic, but little is known about variation in individual physiological responses at rest. We have previously shown that the ingestion of caffeine with sugar increased the rate of carbon dioxide production more than when sugar alone was consumed. Objective: The aim of this study was to determine the effect of the ingestion of caffeine, sugar, and caffeine with sugar on carbon dioxide production and heart rate. Methods: In a crossover three-treatment design, 12 participants reported fasting on three separate days. Treatments were 1.33 mg/kg body weight caffeine only, 0.4 g/kg body weight sugar only, and caffeine with sugar. Breath-by-breath measurements of respiratory gas exchange and heart rate were recorded for 30 min before and after treatments. Data visualization techniques were used to examine the patterns of response. Results: Carbon dioxide production increased or remained the same with all three treatments. Caffeine alone slowed the...
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