Abstract
BackgroundGastrointestinal metastsasis from the breast cancer are rare. We report a patient who presented with intestinal obstruction due to solitary caecal metastasis from infiltrating ductal carcinoma of breast. We also review the available literature briefly.Case presentationA 72 year old lady with past history of breast cancer presented with intestinal obstruction due to a caecal mass. She underwent an emergency right hemicolectomy. The histological examination of the right hemicolectomy specimen revealed an adenocarcinoma in caecum staining positive for Cytokeratin 7 and Carcinoembryonic antigen and negative for Cytokeratin 20, CDX2 and Estrogen receptor. Eight out of 11 mesenteric nodes showed tumour deposits. A histological diagnosis of metastatic breast carcinoma was given.ConclusionTo the best of our knowledge, this is the first case report of solitary metastasis to caecum from infiltrating ductal carcinoma of breast. Awareness of this possibility will aid in appropriate management of such patients.
Highlights
Gastrointestinal metastsasis from the breast cancer are rare
We report a lady who presented with intestinal obstruction due to solitary caecal metastasis from infiltrating ductal carcinoma of breast
A histological diagnosis of metastatic breast carcinoma was made in light of the histological pattern of the tumour, previous history of breast cancer, positive immunostaining with CK7 and Carcinoembryonic Antigen (CEA) and negative with CK20 and CDX2
Summary
Metastasis from the breast cancer to the gastrointestinal tract is rare. Presentation of such patients can mimic that of primary bowel neoplasm and the exact diagnosis is often only made on detailed immunohistochemical study. She reported a significant weight loss over past few months Her relevant past history included rheumatoid arthritis and pT1 N0 M0 carcinoma of the right breast, 3 years ago, for which she underwent wide local excision and axillary node sampling followed by adjuvant radiotherapy. She was on Arimidex as hormonal therapy. A histological diagnosis of metastatic breast carcinoma was made in light of the histological pattern of the tumour, previous history of breast cancer, positive immunostaining with CK7 and CEA and negative with CK20 and CDX2
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