Abstract
Cadmium has been suggested as a potential etiologic agent in human hypertension and has been reported to induce hypertension in experimenta animals. Cadmium acetate was administered ip to Sprague-Dawley derived and hooded Long-Evans rats at several dose levels and under a variety of treatment schedules and conditions. Under none of these circumstances was hypertension produced. These findings indicate that cadmium does not act as a proximate hypertension-inducing agent under all experimental conditions.
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