Abstract
Computer-aided detection (CAD) systems that attract the reader's attention to potentially suspicious features on a mammogram are now in clinical use in screening mammography in the USA and some European countries. However, recent publications have debated the benefit of CAD systems in screening mammography and have highlighted the need for robust evidence from prospective randomised trials. The evidence from these studies will be reviewed, including a recently published meta-analysis of double reading versus single reading with CAD. The CADET II trial was a prospective multicentre randomised comparison of single reading with CAD and double reading in the UK National Health Service Breast Screening Programme. Over 30,000 women (age 50 to 70 years), attending routine mammo-graphy at three UK breast screening centres, were recruited into the trial. Film batches from screening sessions were randomly assigned in a ratio of 28:1:1 to one of three film-reading regimes: double reading and single reading with CAD, or double reading only, or single reading with CAD only. The primary outcome measures were matched comparisons of the cancer detection rates and the number of women recalled for assessment by the two reading regimes. The results of the study will be presented at the conference. The implications of this study will be discussed together with further work that needs to be undertaken.
Highlights
Breast-sparing oncoplastic procedures (BSOP) offer a predictive marker guiding use of anti-oestrogen therapy, and radical new alternative to mastectomy and conventional breast- expression profiling appears to select patients more or less likely to conserving surgery in early breast cancer treatment
The aim was to document attitudes to male radiographers and the effect on the programme performance parameters through a postal questionnaire completed by 85.8% of a random sample of 2,000 women recently screened by BreastCheck
Nine per cent would not have proceeded if the radiographer was male; 17.5% agreed that ‘If there were male radiographers I would not return for another screening appointment’; and 18.3% were unsure
Summary
Breast-sparing oncoplastic procedures (BSOP) offer a predictive marker guiding use of anti-oestrogen therapy, and radical new alternative to mastectomy and conventional breast- expression profiling appears to select patients more or less likely to conserving surgery in early breast cancer treatment. We have compared the results of screening with analogue and digital technology over our first 2 years, in terms of recall rates, cancer detection rates and positive predictive value, and found no overall significant difference in any of these parameters. Abnormalities are graded as A, B or C at consensus by the radiologists and reporting radiographers depending upon the mammographic likelihood of cancer and biopsy This means that patients can be allocated to one of our three assessment clinics and at specific times within those clinics to facilitate workflow. Methods A retrospective analysis of all breast cancer patients with recurrence who had completed 5 years of follow-up was performed. Infection control is not routinely included in the quality assurance process of all units
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