Abstract

65 patients with end-stage renal disease received seventy-six cadaveric kidney transplants between July 1, 1965, and June 30, 1968. 32 patients are still alive, including 22 patients at more than one year. Of the patients surviving more than a year (including 5 survivors from an earlier series), renal function is steady in 18 and deteriorating in 9; 14 have moderate-to-severe proteinuria. In the 33 fatal cases, sepsis was the most significant contributing factor, followed by ureteric leaks and vascular complications. The duration of peritoneal dialysis, length of " warm " ischæmia-time of the grafted kidney, development of acute tubular necrosis, and the number of blood-transfusions received did not affect kidney function or survival.

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