Abstract
The treatment strategy for cancer cachexia is based on the cachexia stage of the cancer and its phenotypes, therefore interventions and expected outcomes vary. In order for the patient to get the most out of the treatment, it should be done based on the mechanism of intervention and the quality of life of patients should be addressed, including aspects of rehabilitation and reduction of the patient’s suffering using a multidisciplinary team. Given the importance of the subject, the present study aims to investigate cachexia and anorexia in cancer. From the electronic databases, PubMed, Cochrane Library, Embase, Web of Sciences have been used to perform a systematic literature until 2020. Therefore, a software program (Endnote X8) has been utilized for managing electronic titles. Searches were performed with mesh terms. This review recommended that clinicians establish an interaction between cancer anorexia-cachexia syndrome (CACS) treatments and chronic pain treatments and choose the best treatment option.
Highlights
Cancer anorexia-cachexia syndrome (CACS) is a multi-factorial clinical syndrome known as weight loss, tissue wasting, metabolic alterations and increased resting energy expenditure [1]
The treatment strategy for cancer cachexia is based on the cachexia stage of the cancer and its phenotypes, so interventions and expected outcomes vary
Given the importance of the subject, the present study aims to investigate cachexia and anorexia in cancer
Summary
Cancer anorexia-cachexia syndrome (CACS) is a multi-factorial clinical syndrome known as weight loss, tissue wasting, metabolic alterations and increased resting energy expenditure [1]. The quality of life of CACS individuals has been improved by various therapies, such as increase of nutritional supplements, stimulation of appetite, reduction of serum levels of several cytokines, and alleviation of insulin resistance. All these interventions have limitations and there remains no definitive pharmacological therapy to address the. To improve the quality of life of CACS patients, treatment methods such as increasing dietary supplements, stimulating appetite, reducing insulin resistance and reducing the serum level of some cytokines can be used [4]. Given the importance of the subject, the present study aims to investigate cachexia and anorexia in cancer
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