C4 PERMANENT HIS BUNDLE PACING USING STYLET–DRIVEN LEAD IN PATIENTS WITH RIGHT ATRIOMEGALY: A SINGLE–CENTER EXPERIENCE

Abstract

Abstract Background His bundle pacing (HBP) is becoming an increasing widespread approach for physiological pacing. However, successful HBP procedure could be hampered by limited implantation tools especially in challenging anatomies. We aimed to report our experience with HBP technique using a novel stylet–driven lead system in patients with right atriomegaly. Methods Consecutive patients with right atrium (RA) volume >25 mL/m2 in men and >21 mL/m2 in women who underwent permanent HBP for standard indications were enrolled from March 2020 to March 2021. The tool of first choice for HBP attempt was a stylet–driven lead (Solia S 60, Biotronik) delivered via a dedicated introducer sheath (Selectra 3D, Biotronik). The acute, 1–month and 6–month procedural success rate was assessed. Results We enrolled 24 patients (median age 75 [70–79] years, 85% men) with an average RA volume of 50.7±7.8 mL/m2. At implant, conduction system pacing using stylet–driven lead was achieved in 21 patients (87%): 12 (50%) selective HBP, 6 non–selective HBP (25%) and 3 left bundle branch area pacing (12.5%). In the 3 failures, HBP was further attempted with a different system with final procedural success in 2 cases. In the successful cases, there was a significant reduction of QRS duration between paced and spontaneous beats (152.5 (130–167.5) ms vs 130 (122.5– 137.5) ms, p = 0.003). No lead dislodgment nor significant pacing threshold increase was observed at 1–month (1.30±0.76 V@0.4 vs. 1.32±0.80 V@0.4ms, p > 0.9) and 6–month follow–up (1.30±0.76 V@0.4 vs. 1.38±0.97 V@0.4ms, p = 0.66). Conclusions In our experience, the novel stylet–driven lead system showed high implant success rates and capture threshold stability also in patients with right atriomegaly.