Abstract
A C4 haplotype containing C4*A6 without C4*B1 is described. It occurred in the MHC haplotype HLA-A1, Cw5, Bw44, C2*1, BF*S, C4*A6BQO, DR3, GLO 2. This haplotype was observed in five of eight siblings, including the propositus who was in renal failure. The C4A6 was not haemolytically active and this new haplotype is therefore of particular interest since it is functionally equivalent to the rare C4-deficient haplotype C4*AQOBQO.
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