Abstract
Bovine leukemia virus (BLV) and human T-lymphotropic virus type 1 (HTLV-1) are closely related deltaretroviruses that induce hematological diseases. HTLV-1 infects about 15 millions people worldwide, mainly in subtropical areas. HTLV-1 induces a wide spectrum of diseases (e.g. HTLV-associated myelopathy / tropical spastic paraparesis) and leukemia/lymphoma (Adult T cell Leukemia). Bovine leukemia virus is a major pathogen of cattle causing important economic losses due to reduction in production, export limitations and lymphoma-associated death. In the absence of satisfactory treatment for these diseases and besides prevention of transmission, the best option to reduce prevalence of deltaretroviruses is vaccination. We propose a strategy that efficiently protects against BLV infection in herd settings and outline key parameters required for vaccine efficacy.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: JAIDS Journal of Acquired Immune Deficiency Syndromes
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
