Abstract
Thrombotic events in newborns (NB) are rare. The most important known risk factor is the presence of central line catheters. Factor V Leiden (FVL) is considered the most frequent genetic risk factor. Spontaneous thrombotic events are less frequent in NB and may involve CNS and Renal Veins (RV). There is no consensus on recommended laboratory workups nor on treatment protocols (Grade 2C). Different ethnic frequency of thrombophilic genetic factors may influence the incidence of thrombotic events in NB.
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