Abstract

A fast, simple and reliable method for the detection of vitamin C by employing gold nonorods as the sensing platform is proposed on the basis of the shift of localized surface plasmon resonance (LSPR) absorption of gold nanorods resulting from the formation of Au@Ag core/shell nanorods. Under optimum conditions, LSPR gets shifts with the increase of vitamin C in the range of 0.25-10.0 μmol/L and the limit of detection (3σ) is 0.12 μmol/L. The developed method is successfully applied to the determination of vitamin C in troches with the recovery of 95.4%-106.0%, identical with the results measured with China Pharmacopeia.

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