C-reactive protein in eales disease

Abstract

C-reactive protein (CRP) is an acute-phase reactant. A study was undertaken to estimate CRP, by rapid slide latex test, in 32 consecutive cases of Eales disease and 32 matched healthy controls. Elevated levels of CRP were detected in 11 (84.6%) of 13 cases of active disease. The CRP titers ranged from 0.6 to 2.4 mg%. Sensitivity and specificity of this test were 84% and 100%. After oral methotrexate pulsed therapy, elevated levels of CRP returned to normal.