Abstract
Recently, beside high-pathogenic A/H5N1 avian influenza virus, A/H5N6 subtype also dominated and caused out-break of bird flu in central provinces of Vietnam. The surveillance had isolated 11 strains of A/H5N6 among 34 households with sick and/or death poultries, with none of A/H5N1. Analysis of phylogenetic tree showed close association of these A/H5N6 strains with A/common gull/Saratov/1676/2018 isolated in Russia, in 2018. Also, they had similar antigenic characteristics with vaccine candidate strain A/Guangdong/18SF020/2018 (H5N6), as WHO recommendation in 2018. Investigation of virulent among these strains showed A/H5N6 having high pathogenicity and contagious feature with chicken embryos. Surveillance of avian influenza virus in poutries, detection of exchanging, compatible, and interaction of infection between human - poultry, plays important role in forecasting of emerging newly pandemic influenza virus in Vietnam.
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