Abstract
The study is carried out to describe and compare histopathological characteristics of bacillary necrosis disease in striped catfish (Pangasianodon hypophthalmus) and red tilapia (Oreochromis sp.). Diseased samples of striped catfish and red tilapia were collected from cultured ponds/cages and from the experimental infection with Edwardsiella ictaluri. Both diseased striped catfish and red tilapia exhibited the same pathological signs such as stop feeding, lethargic swimming, appearance of round white spots with a diameter of 0.5-3 mm in the internal organs (liver, kidney and spleen). The results of histopathological analysis showed similar characteristics in two fish species, including: (1) many areas of liver, kidney and spleen tissues of diseased fishes displayed congestion, hemorrhage, necrosis and structural changes, (2) pigmented macrophage centers increased in number and size on kidney and spleen tissue. In diseased red tilapia, there were many lipid vacuoles in liver tissue and granulomas on the kidney and spleen.
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