Abstract
Menopause is no walk in the park. Though every person’s experience is different, the often-distressing effects from depleted hormones—including hot flashes, night sweats, and anxiety—lead many to seek treatment. Hormone replacement leads to an increased cancer risk, however, just as continued exposure to natural estrogen increases a woman’s risk of breast cancer as she ages. So, many women turn to natural remedies, such as the botanicals black cohosh and hops. Botanicals have been used as traditional medicines for centuries, but scientific evidence of the extent to which these substances can relieve symptoms without increasing cancer risk varies widely. Judy Bolton, who heads the medicinal chemistry and pharmacognosy department at the University of Illinois, Chicago, aims to understand the mechanisms behind these hormone alternatives, with an eye toward developing improved ones. Bolton delivered the Founder’s Award address at the ACS national meeting in Boston in August in the Division of Chemical
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