ペルシャ湾航路油槽船乗組員のビタミンC代謝についての研究 : 2-6 Dichlorphenolindophenolによる皮内反応時間測定による

Abstract

Seamen on tankerships sailing on the Persian-Gulf Route are always under special conditions in several respects, i.e. especially temperature, food, working time, and working place. The author considered that the saturation of vitamin C in the blood might obviously be influenced by such circumstances. Therefore, the author investigated for 2 years from 1961 to 1963 the saturation degree by measuring the reaction-hour which occurred by intracutaneous injection of 2-6 dichlorphenolindophenol-solution (40 mg/dl). 99 seamen were measured 641 times on board. The results were a follow. 1) The average of the reaction-hour of all cases was 6'50. This means that the results were within normal saturation degree of Vitamin C. Many authors reported that the normal reaction-time was over 6 minutes and within 10 minutes. 2) As to the influence by age, the reaction-time of subjects of 40 years of age, i.e. 5'40, was shorter than any others. That of 30 years of age was 6'50, 20 years of age 7'20, and 50 years of age 7'50. Total average by age was within 10 minutes. 3) As to the influence by season, the reaction-time in summer season, i.e. 6'10, was shorter than any others, without regard to age, position, and kind of work. In spring season it was 6'25, in winter 6'55, and in autumn a little extend to 7'15. 4) As to the influence by working position and working time, the reaction-time of subjects at the engine part was very short, especially in watchmen in engine room it was shortest, being 4'56. Average reaction-time of subjects at the engine part during watchtime was 5'14. Average of all engineer was 6'10, including their rest-time. Whenever we research something about men at engine part on board, it is neccesary to consider the extraordinary high temperature in the engine room. Men at the galley part was also exposed to high temperature and their reaction-time was short, being 5'15. Values of men at other parts were not so short, but within 10 minutes. The author considered that the above phenomenon might be caused by the dilatation tendency of peripheral blood-vessels under such abnormal high temperatures. 5) As to the length of sea service, the reaction-time was not distinctly different from the average value of all cases. It was not recognized that in accordance with the length of sea service the reaction-time became more extended. 6) Comparison of ordinary cases with control cases showed that in the later it was just 1 minute shorter than in the former. Average time of control cases (97 cases) was 5'56.