Bwamba fever virus and Semliki Forest virus in young dogs.

Abstract

1. A strain of Semliki Forest virus passaged intracerebrally in Swiss albino mice has been successfully transmitted intraperitoneally and intracerebrally to mongrel puppies. 2. Puppies exposed by intacerebral, intranasal, intradermal, intraperitoneal, and intracardial routes to Bwamba Fever virus and puppies exposed by intranasal, intradermal, and intracardial routes to Semliki Forest virus showed clinically no signs of nervous symptoms, and mice injected intracerebrally with brain suspensions from these puppies showed no evidence of Bwamba Fever or Semliki Forest disease.