Abstract
Introduction: Today, intermediate-weighted (IW) and T2-weighted (T2w) Turbo Spin Echo (TSE) sequences with fat suppression are most commonly used to clinically assess morphological abnormalities of joint structures. In addition, quantitative analysis of the musculoskeletal system using MR relaxometry techniques such as T2 mapping has gained interest in recent years. This is in particular the case for imaging of osteoarthritis, since T2 values can be used as a non-invasive biomarker of early degenerative disease of cartilage and meniscus. The acquisition of both morphological and quantitative sequences is however time consuming. We suggest using a fast quantitative T2 mapping technique that allows the generation of synthetic images with different TEs, allowing a significant decrease in acquisition time while preserving image quality in comparison to the consecutive acquisition of morphological and quantitative sequences.
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