Abstract
Sera from patients with polycythemia vera without prior cytostatic therapy stimulate the growth of bursts during in vitro methylcellulose cultures of peripheral mononuclear cells from normal donors. Sera from patients with polycythemia vera in remission after treatment with 32P or cyclophosphamid, did not significantly stimulate the growth of bursts during incubation with normal peripheral mononuclear cells. The stimulating factor was demonstrable again in patients during relapse.
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