Burkitts’s lymphoma – an atypical presentation

Farah Ziade,Nicolas Von Der Weid,Andreas Nydegger,Maja Beck-Popovic

doi:10.1186/1471-2431-12-113

Farah Ziade, Nicolas Von Der Weid + Show 2 more

Open Access

https://doi.org/10.1186/1471-2431-12-113

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Abstract

BackgroundIn female adolescents and young adults, malignancies of the genital tract are the most frequent type of cancer, closely followed by Hodgkin’s and non-Hodgkin’s lymphomas.Case PresentationWe report an unusual case of sporadic Burkitt’s lymphoma (BL) presenting with massive bilateral ovarian infiltration, peritoneal carcinomatosis and diffuse nodular lesions of the stomach and the intestine mimicking Krukenberg tumor. Diagnostic biopsies were obtained by endoscopy of the upper gastrointestinal tract. With intensive chemotherapy, complete remission was rapidly achieved, without life-threatening tumor lysis syndrome.ConclusionBesides metastatic gastric adenocarcinoma, BL is an important differential diagnosis in adolescents presenting with Krukenberg tumor.

Highlights

In female adolescents and young adults, malignancies of the genital tract are the most frequent type of cancer, closely followed by Hodgkin’s and non-Hodgkin’s lymphomas
Suspecting obstructive endoluminal masses, an upper endoscopy was performed and revealed multiple, large (2 to 3 cm in diameter), raised ulcerated tumors involving the stomach, as well as multiple similar lesions throughout the duodenum and jejunum (Figure 2); multiple biopsies were taken from several lesions for further analysis
Similar reports have only been described in adult female patients, where gastric adenocarcinoma was the underlying disease [2,3]

Summary

Introduction

In female adolescents and young adults, malignancies of the genital tract are the most frequent type of cancer, closely followed by Hodgkin’s and non-Hodgkin’s lymphomas. Case presentation A 15 year old girl presented to our outpatient clinic with a one month history of abdominal pain, vomiting, nausea, early satiety and weight loss of 3 kg. No palpable abdominal mass was detected clinically but ultrasonography revealed huge bilateral ovarian masses, suggestive of Krukenberg tumor.

Results

Conclusion