Burkholderia gladioli keratitis associated with consecutive recurrent endophthalmitis.

Abstract

To report a case of Burkholderia gladioli keratitis with consecutive endophthalmitis. Case report and literature review. A 76-year-old man with a history of diabetes mellitus developed bacterial keratitis and consecutive endophthalmitis in the corneal graft of the left eye. Corneal, aqueous, and vitreous cultures yielded Burkholderia gladioli. Emergent keratoplasty, pars plana vitrectomy, and injection of intravitreal antibiotics led to resolution of the infection and improved vision. Four months later, the patient developed recurrent Burkholderia keratitis and endophthalmitis, necessitating a total keratoplasty and repeat injection of intravitreal antibiotics. This is the first report, to our knowledge, of ocular Burkholderia gladioli infection, an uncommon aerobic, gram-negative rod, recently subclassified from the genus Pseudomonas based on DNA-rRNA homology studies.