Burden of Leptospirosis in Cambodia: preliminary results of an incidence study

Abstract

Background: Recent reports of specific patient groups have eported a decrease in inappropriate prescribing of antibiotics for espiratory tract infections of viral origin. However, no research has een published evaluating if these reports translate to dispensed rescriptions nationally throughout the United States (U.S.). Methods: Prescriptions for systemic antibiotics dispensed rom 7/1/2009-6/30/2011 were extracted from the IMS Health© ponent® database, containing 70% of all prescriptionmedications rojected to a national total.We compared the number of prescripions dispensed in the community between two 12 month periods n the overall population and by state and region. Results: 523.6 million antibiotic prescriptions were utilized rom 7/1/2009-6/30/2011. Prescriptions increased by 1.9% in 010-2011 (264.2 million) when compared to 2009-2010 (259.4 illion). When adjusted for population, 0.84 prescriptions were tilized/capita in 2009-2010 and 0.85 in 2010-2011. Regional rowth in the total number of prescriptions was highest in the idwest (3.5%), followed by the West (2.75%), Northeast (1.23%) nd South (0.82%). Sixteen states experienced > 4% growth durng the study period: Iowa (7.6%),Wisconsin (7.0%), andMinnesota 7.0%) had the greatest increases. Ten states experienced a decrease n antibiotic prescriptions dispensed: Arkansas (5.2% decrease), hode Island (4.9%), and Massachusetts (2.8%) had the greatest ecreases. When adjusted for population, use was highest in the idwest during the study period (2009-2010=0.0.91 Rx/capita; 010-2011=0.90) and lowest in the West in 2009-2010 (0.77) and he Northeast in 2010-2011 (0.82). Conclusion: In the United States, antibiotic use had a minimal ncrease from 2010-2011 as compared to 2009-2010. Geographic rends were also observed but these differences narrowed in 2011.