Burden of disease of colorectal cancer in the Chinese population, in 1990 and 2013

Abstract

To analyze the disease burden of colorectal cancer in the Chinese people in 1990 and 2013. Data from the estimation of 2013 Chinese Sub-national Burden of Disease Study was used, to analyze the incidence and mortality of colorectal cancer in China, in 1990 and 2013, among all the Chinese people. Data on the years of lifte lost due to premature mortality (YLL), years lived with disability (YLD) and disability-adjusted life years (DALY) of colorectal cancer in China, in 1990 and 2013 was also used. Related death rates, DALY and DALY rates were compared. The standardized incidence rate of colorectal cancer among Chinese people increased by 66.83% from 12.15/100 000 in 1990 to 20.27/100 000 in 2013 (72.82% for men and 55.26% for women). The standardized mortality rate of colorectal cancer increased by 4.73% from 10.57/100 000 in 1990 to 11.07/100 000 in 2013 (with 9.03% increase for men but 3.12% decrease for women). A total number of 148 000 people died from colorectal cancer in 2013, with an increase of 90.08% (105.36% for men and 72.14% for women) compared with the number of 77 900, in 1990. Related data on DALY, YLL and YLD due to colorectal cancer appeared as 3 331.6 thousand person years, 3 200.7 thousand person years and 130.9 thousand person years, respectively in 2013, with YLL as the vast majority of DALY. Compared with 2 019.1 thousand person years in 1990, DALY showed an increase of 65.01% in 2013. However, the standardized DALY rate reduced by 6.00% from 238.54/100 000 in 1990 to 224.23/100 000 in 2013. Parameters as the mortality rates, DALY and DALY rates appeared all higher in men than in women, in every age group. The disease burden of colorectal cancer in China remained at high levels in 2013. Compared with the data in 1990, the total disease burden on colorectal cancer showed an increase while the DALY rate and YLL rate showed a decline in 2013.