Burden of Cardiogenic Shock In Patients With Takotsubo Syndrome: A National Perspective

Abstract

Introduction There is limited data on the incidence of cardiogenic shock (CS) among patients with Takotsubo Syndrome (TTS). We aimed to study the incidence, predictors and outcomes of CS in patients with TTS. Methods We used the National Inpatient Sample (NIS) database from September 2006 to December 2017 to identify all patients with TTS using the appropriate diagnostic codes. Patients with TTS were divided into those with and without CS and the two groups were compared in regard to demographics, medical comorbidities, resource utilization, cost of hospitalization and length of stay. Logistic regression analysis was used to identify predictors of CS in patients with TTS. Results A total of total of 265,423 patients with TTS were included in our study, of whom 14703 (5.5%) were diagnosed with cardiogenic shock (CS). TTS Patients with CS were more likely to be younger (67, IQR [56.6-75] years vs 68, IQR [58-78] years), males (20.9% vs 13.8%, P Conclusion In hospital mortality among TTS patients with CS was approximately five-fold higher compared to those without CS (22.9% vs 4%, p