Abstract
Introduction: Thalassemia encompasses a group of genetic blood disorders, in which there is altered or inadequate haemoglobin synthesis and requires a repeated blood transfusion. Due to repeated blood transfusion, these patients are vulnerable to HCV, HBV, and HIV like blood transfusion transmitted diseases. Aims and Objective: To determine the prevalence of HCV and HBV infections in multitransfused thalassemia patients in a tertiary care hospital. Material And Methods: Cross sectional and observational studywas done on a total of 110 beta thalassemia patients aged between 2-25years &were categorised into four groups (2-7 years, group 1; 8-13 years, group 2; 14-19 years, group 3 and 20-25 years, group 4).For testing, 5 ml Blood sample was collected, Serum separatedand subjected to testing for HBsAg, and antibody to Hepatitis C, by ELISA method. Screening was done by immunochromatography test (point of care test). Results: A total of 110 patients of beta thalassemia major were included in our study. Out of this, 68(62%) were males and 42(38%) were females.
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