Burden and Epidemiology of Influenza- and Respiratory Syncytial Virus-Associated Severe Acute Respiratory Illness Hospitalization in Madagascar, 2011-2016

Joelinotahina H Rabarison,Julia Guillebaud,Norosoa H Razanajatovo,Stefano Tempia,Aina Harimanana,Jean-Michel Heraud,Maherisoa Ratsitorahina

doi:10.1111/irv.12607

Abstract

Burden and Epidemiology of Influenza- and Respiratory Syncytial Virus-Associated Severe Acute Respiratory Illness Hospitalization in Madagascar, 2011-2016

Highlights

We reported national and provincial estimates of influenza-and respiratory syncytial virus (RSV)-associated severe acute respiratory illness (SARI) hospitalization in Madagascar over a 6-year period
Influenza-and RSV-associated SARI hospitalizations were substantial with those associated with RSV infection being the highest
Whereas SARI hospitalizations associated with both pathogens were observed across age groups, a differential burden among patients of different age was observed with children aged

Summary

Background

Influenza and respiratory syncytial virus (RSV) infections are responsible for substantial global morbidity and mortality in young children and elderly individuals. Estimates of the burden of influenza-and RSV-associated hospitalization are limited in Africa. Results: Overall, the mean annual national number of influenza-associated SARI hospitalizations for all age groups was 6609 (95% CI: 5381-7835-rate: 30.0; 95% CI: 24.4-35.6), 4468 (95% CI: 3796-5102-rate: 127.6; 95% CI: 108.4-145.7), 2141 (95% CI: 1585-2734-rate: 11.6; 95% CI: 8.6-14.8), and 339 (95% CI: 224-459-rate: 50.0; 95% CI: 36.3-74.4) among individuals aged

| INTRODUCTION

| METHODS

| DISCUSSION

Findings

CONFLICT OF INTERESTS