Bullous disease in infant: think of cutaneous mastocytosis

Abstract

Mastocytosis is a rare disease. The cutaneous form is the most frequent. There are several clinical forms of cutaneous mastocytosis including the bullous form which is rare. We report a case of a 16-month-old girl, presented pruriginous lesions, evolving since the age of 10 months, treated as bullous impetigo 2 times without improvement. The examination clinic had found post-bullous erosions, resting on healthy skin on the trunk; with hypo-pigmented cicatricial macules, Darier´s sign and dermographism were positive. There were no other extra-cutaneous signs. Histology favored cutaneous mastocytosis in its bullous form.