Abstract
Implantable medical devices are widely used, but biomaterial-associated infections (BAIs) impose a huge economic burden and increase the mortality of patients. Therefore, BAIs are a serious concern that must be urgently resolved. Materials with antibacterial properties have become hotspots of current research and development. In the present work, quaternized chitosan (QCS) is used as an antibacterial agent and blended with thermoplastic polyurethane (TPU) to create an antibacterial material for tracheal intubation tubes. The modified TPU material (QCS-TPU) exhibited good mechanical properties and excellent long-term antibacterial performance. Under in vitro hydrodynamic conditions, QCS-TPU retained its strong antibacterial properties. QCS-TPU also possessed a low hemolysis rate and cytotoxicity. The current work is expected to provide a facile and feasible strategy for the preparation of antibacterial catheters and aid in the discovery of promising clinical applications to prevent BAIs.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
