Budesonide nebulization added to systemic prednisolone in the treatment of acute asthma in children: a double-blind, randomized, controlled trial.

Abstract

AA Alangari, N Malhis, M Mubasher. Chest. 2014;145(4):772–778 The goal of the study was to test the hypothesis that adding high-dose nebulized budesonide to standard asthma treatment in children in the emergency department (ED) during the first hour would decrease their hospital admission rate. The study population included children aged 2 to 12 years with physician-diagnosed asthma (or previous episodes of shortness of breath responsive to a β-agonist) who presented to the ED with a moderate or severe acute asthma exacerbation. Children were randomized within …