Abstract

Background: Respiratory distress syndrome (RDS) is an important cause of morbidity and mortalityin preterm infants. Bubble CPAP when used appropriately, is more cost-effective, non-invasive,requires less training and has a lower risk of complications. However, not all preterm infants withRDS respond to CPAP. Aims: To study the immediate outcome of preterm infants with mild tomoderate respiratory distress syndrome on Bubble CPAP. To study the safety and effectiveness of B-CPAP and to identify the risk factors associated with its failure. Setting: NICU, Department ofpediatrics, Mamata general hospital and medical college, Khammam. Design- Prospectiveobservational study Material and Methods: This duration bound study was conducted fromFebruary 2018 to February 2020. Based on the inclusion criteria 73 Preterm babies with mild tomoderate respiratory distress syndrome requiring respiratory support were included in this study.Details of birth history, use of antenatal steroids, gestational age, type of delivery, birth weight,Downes score and chest X-ray were recorded. And the effectiveness and outcome of bubble CPAPwere studied. Results: Out of the total of 73 cases, 53(72.60%) were treated successfully, while20(27.40%) failed bubble CPAP. Conclusion: Bubble CPAP is the safe primary mode of respiratorysupport in Preterm newborns with mild to moderate RDS, more effective with early Initiation and inPreterm babies born to mothers with the use of antenatal steroids.

Highlights

  • Respiratory distress syndrome (RDS) is an important cause of morbidity and mortality in preterm Newborn [1]

  • Bubble continuous positive airway pressure (CPAP) is the safe primary mode of respiratory support in Preterm newborns with mild to moderate RDS, more effective with early Initiation and in Preterm babies born to mothers with the use of antenatal steroids

  • The objective of the study was to evaluate the outcome in preterm newborns (28 to 37 weeks of gestational age) with mild to moderate respiratory distress syndrome on Bubble CPAP and to determine the risk factors associated with failure of B-CPAP

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Summary

Introduction

Respiratory distress syndrome (RDS) is an important cause of morbidity and mortality in preterm Newborn [1]. Current modalities of ventilatory assistance in the management of respiratory distress syndrome (RDS) in preterm infants range from continuous positive airway pressure (CPAP) to various modes of mechanical ventilation [2]. The objective of the study was to evaluate the outcome in preterm newborns (28 to 37 weeks of gestational age) with mild to moderate respiratory distress syndrome on Bubble CPAP and to determine the risk factors associated with failure of B-CPAP. Aims: To study the immediate outcome of preterm infants with mild to moderate respiratory distress syndrome on Bubble CPAP. Conclusion: Bubble CPAP is the safe primary mode of respiratory support in Preterm newborns with mild to moderate RDS, more effective with early Initiation and in Preterm babies born to mothers with the use of antenatal steroids

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