Abstract
Two models which describe the oxygen transfer, oxygen uptake, and axial mixing in a bubble column fermenter are described. Model I includes no pressure effects and can be solved analytically. Model II incorporates the influence of hydrostatic pressure on oxygen solubility and gas expansion and must be solved numerically. The liquid phase oxygen concentration profiles as obtained from both models are compared to ascertain for what parametric conditions and for what maximum column height Model I is valid. The results show that for many situations Model I can approximate the oxygen profiles in a 10 m column within 20%. As the transfer and uptake rates increase the deviation of Model I can reach 80% for a 10 m column.
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