BS9 Long QT syndrome-associated calmodulin mutations affect interaction with L-type CA2+ channel (CAV1.2) and camkIIδ activity

Abstract

IntroductionCatecholaminergic polymorphic ventricular tachycardia (CPVT) and Long QT Syndrome (LQTS) are two major inherited lethal cardiac channelopathies responsible for sudden death predominantly among the young population. Of late, mutations in...