Abstract
Adult Aedes aegypti axenically reared on a chemically defined dietary medium had low infectivity to Brugia pahangi, and harbored few third-stage parasitic juveniles. Some of these parasites appeared not to have completed the second molt at the end of 10 days of incubation. Mortality was high in mosquitoes from axenic larval rearings, especially during filarial infection. It appeared probable that adverse effects on the worm resulted from suboptimal host nutrition. Thus, manipulations of the chemically defined dietary medium used to rear A. aegypti may be used to study the influence of specific nutrients on filarial development.
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