Abstract
Background:Mycotic cerebral aneurysms are uncommon. We intend to report the first case of multiple mycotic cerebral aneurysms due to Brucella infection that were treated surgically.Case Description:A 34-year-old man with neurobrucellosis presented with intracerebral haemorrhage (ICH). Three mycotic aneurysms were detected in the vicinity of middle cerebral artery (MCA). Medical treatment failed to treat them and aneurysms had to be managed surgically.Conclusion:Brucella-related cerebral mycotic aneurysm has rarely been reported. This is the first report of three mycotic aneurysms occurring in a young man with neurobrucellosis treated surgically.
Highlights
ConclusionBrucella‐related cerebral mycotic aneurysm has rarely been reported. This is the first report of three mycotic aneurysms occurring in a young man with neurobrucellosis treated surgically
Brucellosis is one of the most common zoonotic infections around the globe.[9]. It is a multi‐systemic disease which can present with different clinical pictures
The inflammatory processes involving intracranial vessels may lead to lacunar infarcts, venous thrombosis, small hemorrhages, or aneurysm formation.[1,12]
Summary
Brucella‐related cerebral mycotic aneurysm has rarely been reported. This is the first report of three mycotic aneurysms occurring in a young man with neurobrucellosis treated surgically. Four‐vessel digital subtraction angiography (DSA) showed a left distal middle cerebral artery (MCA) aneurysm that was 12 × 9 mm in diameter and without an identifiable neck [Figure 3]. This aneurysm was visible in both anteroposterior (AP) and lateral views even though there were two other ill‐defined aneurysm blebs only seen in the lateral view of the angiogram. All of the preclinical studies were negative except for the following: erythrocyte sedimentation rate (ESR) =28, C‐reactive protein (CRP) =3 plus, and positive serology His general condition improved moderately after 3 weeks of antibiotic therapy (MRS 3), but intermittent fever persisted and the CSF picture did not change notably. The anti‐brucella medications were continued for another 6 weeks and negative serology tests
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