Abstract

Brucellosis is a common zoonotic infection that carries a high economic burden in China especially in Xinjiang. Purpose of the message:To discuss the treatment of brucella infection following total joint arthroplasty and find out its curative effect. Methods. We analyzed 8 patients with who infected joint brucella after received arthroplasty in our department from March 2009 to March 2019, whose ages were from 55 to 79 years old (average age was 65.6 ± 1 years). The following parameters were measured in the pre- and post-operation periods: HSS and Harris score, range of knee motion (ROM), VAS, erythrocyte sedimentation rate (ESR) and C-reactive Protein (CRP). From x-ray to find out post-operate curative effect of revision operation. Results. All cases had pain and elevated ESR. Deep vein thrombosis (DVT) and nerve damage were not found in these cases. There were no sinuses on the skin have be found. All patients received total joint arthroplasty and infected with brucella post operation receive revision operation at last. All cases were followed-up for 6-30 months; the average follow-up period was14 ± 0.5 months. Post operation we took an HSS and Harris score and X-rays to find out its curative effect after revision operation. There were also no patients with aseptic loosening or fracture of prosthesis during or post- revision operation, no recurrence had been found. The average ROM of knee was improved to 90 ± 3°. Conclusions. Recent clinical results indicate that systemic antibrucellosis chemotherapy and surgery technical is effective to treat the patients following. Revision operation can significantly improve the function of the joint and relieve pain.

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