Abstract
IntroductionBrown tumors are rare focal giant-cell lesions that arise as a direct result of the effect of parathyroid hormone on bone tissue in some patients with hyperparathyroidism. Brown tumors can affect the mandible, maxilla, clavicle, ribs, and pelvic bones. Therefore, diagnosis requires a systemic investigation for lesion differentiation.Case presentationWe present a 42-year-old Greek woman, with a rare case of brown tumor of the maxillary sinus due to primary hyperparathyroidism. Primary hyperparathyroidism is caused by a solitary adenoma in 80% of cases and by glandular hyperplasia in 20%.ConclusionsDifferential diagnosis is important for the right treatment choice. It should exclude other giant cell lesions that affect the maxillae.
Highlights
Introduction: Brown tumors are rare focal giant-cell lesions that arise as a direct result of the effect of parathyroid hormone on bone tissue in some patients with hyperparathyroidism
Case presentation: We present a 42-year-old Greek woman, with a rare case of brown tumor of the maxillary sinus due to primary hyperparathyroidism
Regression and healing of the lesions are expected after the correction of hyperparathyroidism, but several cases have been reported of brown tumors that grew after parathyroidectomy or normalization of hyperparathyroidism levels [10]
Summary
The lesions localize in areas of intense bone resorption, and the bone defect becomes filled with fibroblastic tissue These tumors have a brown or yellow hue [1]. Radiolucent, and boneexpanding lesion in the facial bones of a patient with hyperparathyroidism is presented, a brown tumor must be considered to be the most likely diagnosis [1,2]. Her head and neck were normal; no cervical masses were palpated. The concentrations of IgG, IgA, and IgM were normal This suggested the diagnosis of primary hyperparathyroidism initially manifesting as a brown tumor of the maxilla.
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