BROWN TUMOR OF PRIMARY HYPERPARATHYROIDISM ASSOCIATED WITH ECTOPIC PARATHYROID TISSUE

Abstract

This study presents an unusual case of primary hyperparathyroidism with a brown tumor caused by ectopic parathyroid tissue within the mediastinum. A 48-year-old male was admitted, complaining of a painful and hemorrhagic swelling in the anterior mandible, of unknown duration. The patient's medical history was uneventful. Spiral computed tomography revealed well-defined multilocular radiolucencies located within the anterior and body of the mandible, bilateral mastoid processes, and temporal bone, causing significant cortical expansion and thinning. An incisional biopsy of the anterior mandible showed a central giant cell lesion, and laboratory exams detected high values of parathormone, alkaline phosphate, and calcium. Further sestamibi-SPECT parathyroid scintigraphy was carried out and hyperfunctioning ectopic parathyroid tissue within the mediastinum region was detected. The patient was referred to an endocrinologist and is being prepared for thoracic surgery for analysis of the ectopic parathyroid tissue. This study presents an unusual case of primary hyperparathyroidism with a brown tumor caused by ectopic parathyroid tissue within the mediastinum. A 48-year-old male was admitted, complaining of a painful and hemorrhagic swelling in the anterior mandible, of unknown duration. The patient's medical history was uneventful. Spiral computed tomography revealed well-defined multilocular radiolucencies located within the anterior and body of the mandible, bilateral mastoid processes, and temporal bone, causing significant cortical expansion and thinning. An incisional biopsy of the anterior mandible showed a central giant cell lesion, and laboratory exams detected high values of parathormone, alkaline phosphate, and calcium. Further sestamibi-SPECT parathyroid scintigraphy was carried out and hyperfunctioning ectopic parathyroid tissue within the mediastinum region was detected. The patient was referred to an endocrinologist and is being prepared for thoracic surgery for analysis of the ectopic parathyroid tissue.