Brown-Séquard Syndrome Secondary to Spontaneous Bleed from Postradiation Cavernous Angiomas: Fig 1.

M.S Mathews,M Brant-Zawadzki,W.W Peck

doi:10.3174/ajnr.a1158

Abstract

The spontaneous occurrence of acute Brown-Séquard syndrome is an extremely rare event, with most reported cases being secondary to spontaneous epidural hematomas and spinal cord ischemia. We report a rare case of Brown-Séquard syndrome from spontaneous intraspinal hemorrhage in a patient with multiple cavernous angiomas in the spinal cord secondary to craniospinal radiation in childhood. Postulated mechanisms leading to the condition include postradiation molecular changes and venous occlusion.

Highlights

We report a rare case of Brown-Sequard syndrome from spontaneous intraspinal hemorrhage in a patient with multiple cavernous angiomas in the spinal cord secondary to craniospinal radiation in childhood
Case Report A 27-year-old man presented to the emergency department with 2 days of mild weakness in his left arm and leg and numbness and tingling in his right leg that rapidly worsened in the preceding few hours. His medical history included childhood acute lymphocytic leukemia, for which he was treated with chemotherapy and craniospinal radiation therapy between the ages of 3 and 8 years
The intraspinal hemorrhage arose from postradiation cavernous angiomas

Summary

CASE REPORT

Brown-Sequard Syndrome Secondary to Spontaneous Bleed from Postradiation Cavernous Angiomas. We report a rare case of Brown-Sequard syndrome from spontaneous intraspinal hemorrhage in a patient with multiple cavernous angiomas in the spinal cord secondary to craniospinal radiation in childhood. Case Report A 27-year-old man presented to the emergency department with 2 days of mild weakness in his left arm and leg and numbness and tingling in his right leg that rapidly worsened in the preceding few hours His medical history included childhood acute lymphocytic leukemia, for which he was treated with chemotherapy and craniospinal radiation therapy between the ages of 3 and 8 years.

Discussion

Conclusion