Abstract
There has been considerable recent interest in the concept that thermogenesis in brown adipose tissue (BAT) may play an important role in the regulation of energy balance, in addition t o its traditional role in the generation of heat for thermoregulatory purposes. This interest has stemmed primarily from studies on the metabolic responses t o voluntary overfeeding in rats given a ‘cafeteria’ diet, and from investigations on the efficiency of energy utilization of various types of obese animal, particularly genetically obese rodents (for reviews see Rothwell & Stock, 1983; Trayhurn, 1984). The main focus has been on providing an explanation for tlie causes of obesity, but consideration of the importance of BAT in whole-body energy metabolism has now extended to other situations. In particular, the activity of BAT during pregnancy and lactation in rodents is currently being investigated in relation t o the overall energetics of reproduction.
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