Abstract
Brooke-Spiegler syndrome is a rare entity. It is an autosomal dominant syndrome in which multiple trichoepitheliomas, cylindromas, or other adnexal tumors are seen. Very few cases of Brooke-Spiegler syndrome are reported in the literature. We came across a 40 -year-old female in which multiple trichoepitheliomas and cylindromas were seen on scalp. In view of clinical history and histopathological examination it was diagnosed as Brooke-Spiegler syndrome. We report this case because of its rarity.
Highlights
Brooke-Spiegler syndrome was reported for the first time in 1842 by Ancell [1]
More than 50 cases of Brooke-Spiegler syndrome are reported in the literature so far
Features favouring cylindroma included islands of basaloid cells surrounded by hyalinized material
Summary
Brooke-Spiegler syndrome was reported for the first time in 1842 by Ancell [1]. It is an autosomal dominantly inherited syndrome, characterised by multiple skin appendageal tumors [2]. More than 50 cases of Brooke-Spiegler syndrome are reported in the literature so far
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
