Abstract
PURPOSE: The success of radiation therapy for lung cancer treatment is limited by tumor motion during breathing and thus the ability to target effectively. Real-time localization and tracking may enable increased tumor radiation and decreased healthy tissue irradiation. Real-time localization of implanted gold fiducials is limited by high doses of non-therapeutic imaging radiation, expensive fluoroscopic equipment, subjective image interpretation and poor implant stability. A real-time, non-ionizing, objective, electromagnetic localization system that uses wireless implanted Beacon® transponders has been developed (Calypso Medical, Seattle, WA). We compared bronchoscopic implant feasibility and stability for both transponders and gold fiducials in peripheral airways of canine lungs.
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