Abstract
The preceding chapters have demonstrated that bronchoalveolar lavage provides a useful model for the study of human mast cell function. Briefly, bronchoalveolar mast cells respond to IgE-dependent challenge with histamine release and in association with other cells in the bronchoalveolar population are capable of IgE-dependent generation of leukotriene C4 and prostaglandin D2. In addition, mediator release can be inhibited by a variety of anti-allergic compounds. One of the major advantages of the bronchoalveolar mast cell preparation over human dispersed lung mast cells is that bronchoalveolar cells can be recovered by lavage of subjects with diverse underlying diseases allowing the study in vitro of the function of mast cells from different pathological conditions.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
