Bronchial obstructive syndrome in primary infection with Mycobacterium tuberculosis in children

Abstract

Рurpose. The aim is to study the influence of primary Mycobacterium tuberculosis infection on the occurrence of bronchial obstruction syndrome in children. Materials and methods. A retrospective study of primary medical records of 60 children aged 2 to 6 years for the period from 2016 to 2018, with diagnoses of acute obstructive bronchitis and acute respiratory infection. The patients were divided into 2 groups: group I — 30 children with bronchial obstruction syndrome, II group — 30 people — children with common cold without bronchial obstruction syndrome (control group). We studied the dynamics of reactions to the Mantoux test with 2 TE, contacts with tuberculosis patients, the effectiveness of Vaccinum tuberculosis (BCG-M) vaccination, allergological history, the nature of feeding and allergizing factors in everyday life. Data processing was performed using the NanoStat 1.6 program. Тhe сritical level of statistical significance was assumed to be p < 0.05. Results. It was found that primary Mycobacterium tuberculosis (MBT) infection in children under 4 years has a direct correlation with a high risk of bronchial obstruction syndrome. At the same time, bronchial obstruction syndrome occurred in the absence of local tuberculosis, which can be considered as a paraspecific reaction in the case of primary MBT infection. Сonclusions. The observed relationship between the two phenomena determines the need to examine young children with bronchial obstruction syndrome for MBT infection.