Bronchial artery embolization for the treatment of haemoptysis in pulmonary hypertension.

Abstract

To test the efficacy of bronchial artery embolization (BAE) to treat haemoptysis in pulmonary hypertension (PH). 33 patients were treated by BAE for haemoptysis associated with PH (PH group=21) or non-associated with PH (control group=12). The details of procedure, outcome, and rate of relapse were compared between the two groups. Within the PH group, the comparison was operated between subjects with congenital heart disease-associated pulmonary artery hypertension (CHD-APAH subgroup=12) and non-CHD (non-CHD-APAH subgroup=9). The rate of relapse at 30 and 90-days was similar between the PH group and control group. BAE in the PH group was more challenging (median 2 arteries embolized per procedure) compared to the control group (median 1 artery embolized per procedure; p=0.001). Bleeding arteries were more heterogeneous in the PH group, while a single right bronchial artery was the only clinical finding in 66.7% of controls (p=0.001). Within the PH group, the CHD subgroup showed higher survival rate compared to the non-CHD-APAH group (p=0.007). BAE is effective and safe for the treatment of haemoptysis in PH, yet more challenging than other conditions. In PH-associated haemoptysis, BAE provides higher survival rate for subjects with PH associated with CHD.