Abstract
Novel photosensitizers with high reactive oxygen species generation and precise targeting to tumors are crucial for photodynamic therapy (PDT). Here, a bromo-substituted diketopyrrolopyrrole derivative (2,5-bis(6-bromohexyl)-3,6-bis(5-bromothiophene-2-yl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione)-grafted hyaluronic acid is synthesized, which presents excellent targeting and PDT efficiency both in vitro and in vivo.
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