Abstract
Bromelain is a mixture of enzymes found in crude extract from the fruit and other parts of the pineapple Ananas comosus (Linn.), Bromeliaceae family. Bromelain is a nontoxic compound having various industrial and therapeutic applications. It consists of varied closely related proteinases that are important as anti-inflammatory, antithrombotic, and fibrinolytic agents. Bromelain is widely administered for its well-known properties, such as anticancer activity, antioxidant activity, and immunomodulatory effects. It also plays a major role in the modulation of the immune system and prevents the harmful effects of the cytokine storm. Because of all these therapeutic effects, bromelain appears to be a potential candidate to inhibit and prevent the symptoms of different diseases as well being an effective, natural, therapeutic weapon for the treatment of severe COVID-19 infection.
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