Abstract
Cantilever-enhanced photoacoustic spectroscopy coupled with gas chromatography is used to quantitatively analyze a mixture of alcohols in a quasi-online manner. A full identification and quantification of all analytes are achieved based on their spectral fingerprints using a widely tunable continuous-wave laser as a light source. This can be done even in the case of interfering column/septum bleed or simultaneously eluted peaks. The combination of photoacoustic spectroscopy and gas chromatography offers a viable solution for compact and portable instruments in applications that require straightforward analyses with no consumables.
Highlights
Cantilever-enhanced photoacoustic spectroscopy coupled with gas chromatography is used to quantitatively analyze a mixture of alcohols in a quasi-online manner
We have demonstrated a novel Gas chromatography (GC)-photoacoustic spectroscopy (PAS) hyphenated technique, which offers considerable advantages for analyzing complex mixtures of large molecules, especially in applications that require portability
Already in the present form, GC-PAS offers a detection sensitivity that is on average an order of magnitude better than GC-Fourier transform infrared (FTIR)
Summary
To test our GC-PAS system, we prepared a solution of several alcohols in cyclohexane at about 0.26% mol/mol concentration each. Extracting several samples in 2 min intervals is technically possible even with the current setup, it does not leave enough time for cleaning thoroughly the detector gas cell from a previous sample before a new one arrives This would introduce spectral interference and reduce selectivity, especially at low signal levels. This limit can typically be reached in WM spectroscopy of small molecules when the gas exchange and laser power noise do not significantly affect the measurement. An optimally designed CEPAS detector could improve the detection limits of GC-PAS as much as 2−3 orders of magnitude, resulting in low-pg to sub-pg LODs and surpassing FID performance in terms of detection limits, in selectivity
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
