Abstract
Fungi have been assured to be one of the wealthiest pools of bio-metabolites with remarkable potential for discovering new drugs. The pathogenic fungi, Fusarium oxysporum affects many valuable trees and crops all over the world, producing wilt. This fungus is a source of different enzymes that have variable industrial and biotechnological applications. Additionally, it is widely employed for the synthesis of different types of metal nanoparticles with various biotechnological, pharmaceutical, industrial, and medicinal applications. Moreover, it possesses a mysterious capacity to produce a wide array of metabolites with a broad spectrum of bioactivities such as alkaloids, jasmonates, anthranilates, cyclic peptides, cyclic depsipeptides, xanthones, quinones, and terpenoids. Therefore, this review will cover the previously reported data on F. oxysporum, especially its metabolites and their bioactivities, as well as industrial relevance in biotechnology and nanotechnology in the period from 1967 to 2021. In this work, 180 metabolites have been listed and 203 references have been cited.
Highlights
Fungi are eukaryotic microorganisms that settled mostly in all kinds of environments and have fundamental roles in maintaining the environmental balance [1,2]
Many studies revealed that F. oxysporum showed a remarkable capacity to yield diverse classes of secondary metabolites such as alkaloids, jasmonates, anthranilates, cyclic peptides, cyclic depsipeptides, xanthones, quinones, and terpenoids with various activities such as phytotoxicity, antimicrobial, cytotoxicity, insecticidal, antioxidant, and antiangiogenic
The current review summarized the published data regarding secondary metabolites reported from this fungus and their bioactivities
Summary
Fungi are eukaryotic microorganisms that settled mostly in all kinds of environments and have fundamental roles in maintaining the environmental balance [1,2]. Fusarium is a genus of filamentous fungi that includes many mycotoxin producers, agronomically important plant pathogens, and opportunistic human pathogens [12]. Fusarium oxysporum is the most encountered and economically important species of this genus It includes pathogenic (plant, human, and animal) and non-pathogenic strains that even possess bio-control activity against fungal pests and some insects [27]. It is one of the soil-borne pathogens that causes vascular wilt on many plants, which is characterized by various symptoms, including leaf epinasty, vascular browning, progressive wilting, defoliation, stunting, and plant death [28]. The literature search for this work was performed through a computer search of data on Web of Knowledge, ScienceDirect, SCOPUS, Taylor & Francis, Wiley Online Library, Springer, PubMed, JACS, and Google Scholar
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
