Abstract

Green-emissive carbon nanodots (CDs) with high quantum yield are prepared. The abundant functional groups on the surfaces of CDs can selectively interact with Cu2+. The formed cupric amine complexes induce significant fluorescence quenching. The "on-off" switching can be further adjusted to the fluorescence "on" mode by the introduction of glutathione (GSH), which hinders the interactions between CDs and Cu2+. Based on the fantastic optical behavior of CDs, highly sensitive detection of Cu2+ and GSH can be achieved. Intracellular imaging of the two targets is also validated.

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