Abstract
Rats of two experimental groups were placed in an open-field apparatus for 3–5 spatial exploration, each placement lasting 5min (total duration of 15–25min), and had a significantly greater newborn-neuron survival rate of the granule cells than the control group by evaluating the density of 5-bromo-2′deoxyuridine positive cells in the dentate gyrus. This study suggests that brief spatial experiences are sufficient to enhance the survival rate of newborn neurons.
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